Mitochondria act as a reservoir for the basic amine HIPDM in the lung

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Mitochondria act as a reservoir for the basic amine HIPDM in the lung.

The lungs are a site for the uptake, accumulation, and storage of exogenous basic amines. The compound N-N-N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3 propanediamine (HIPDM) is a basic amine that can be labelled with radioactive iodine and detected by external counting. Intravenously injected 123I-HIPDM is extracted by the human lung, where it is retained in a slowly effluxable pool. ...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 1996

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.96.09112306